Formulation and Evaluation Flaxseed Suppository for management of Hemorrhoids

Author(s)	Komal Vinesh Tupshendre, Vaishali Haribabu Tompe
Country	India
Abstract	The rectal route has proven its worth in terms of achieving successful drug delivery both locally and systematically. Hemorrhoids (also called piles) are swollen veins in the lower rectum or around the anus—similar to varicose veins but in that area. Hemorrhoids affect 50% of adults >50 years. Current therapy includes synthetic antinflammatories and laxatives with side effects. Flaxseed offers a natural alternative combining demulcent, anti-inflammatory, and laxative actions in a single rectal dosage form. A suppository comprises flax as a main active ingredient, administered through the rectal route, used as a laxative, and treatment of haemorrhoids and bacterial infections of the anus. For the formulation of the present invention, the suppository preferably comprises flax in an inert base, which may comprise any suitable inert pharmaceutical carrier. The study aims to formulate and evaluate herbal suppositories using flaxseed mucilage and extract as the primary therapeutic agent, leveraging its anti-inflammatory, demulcent, and laxative properties for local rectal disorders like hemorrhoids, constipation, and inflammation.
Keywords	Flax extract, suppository, Gelatin, Glycerine, Herbal suppository
Field	Medical / Pharmacy
Published In	Volume 17, Issue 5, May 2026
Published On	2026-05-28

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